Phytosome: Phytolipid Drug Delivery System for Improving Bioavailability of Herbal Drugs from Journal of Pharmaceutical Science and Bioscientific Research (JPSBR). 1(3): 1-5.Īmit P, Tanwar YS, Rakesh S and Poojan P.
A review of phytosome technology as a novel approach to improve the bioavailability of nutraceuticals from Int J Adv Res Technol. Antihyperglycemic Activity Studies with Malva Verticillata Leaves from World Journal of Pharmaceutical Research. Diffusion rate testing indicates the diffusion rate of the phytosome system can increase the diffusion rate of allicin when compared to the diffusion rate of allicin in garlic extract.Īkter F and Rahmatullah M. The phytosome system formed has an entrapment efficiency value of 64.8789% with a density of 1.0051 g/mL, the particle size of 270 nm, the zeta potential of -32.55 mV and polydispersion index of 0.571. Determination of the value of the diffusion rate of allicin in the extract and in the phytosome system was carried out using a modified diffusion cell for 420 minutes. Garlic extract phytosome was made using a thin layer hydration method which was then evaluated for its physicochemical properties which included testing of entrapment efficiency, density, particle size, index polydispersity, and zeta potential. In this study, it will be observed the effect of making a phytosome system on the diffusion rate of allicin.
Penetration of allicin can be increased by formulating extracts in the phytosome system. In previous studies, methanol extract of garlic can reduce blood sugar levels in mice at a dose of 400 mg/kg BW. Garlic (Allium sativum L) contains allicin which has the property of reducing blood sugar levels.
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